Introduction
Dexamethasone for asthma is widely used as a synthetic corticosteroid and an anti-inflammatory agent with immunosuppressant effects. It is used for the treatment of a wide range of medical conditions, primarily asthma, some types of cancer, rheumatoid arthritis, and respiratory symptoms related to COVID-19.
What is Dexamethasone?
Dexamethasone for asthma is effective in providing relief from inflammation in the body. It is helpful in curing a wide range of conditions, including inflammation, adrenal issues, asthma, arthritis, allergies, bone marrow problems, skin conditions, and kidney problems. it is an oral corticosteroid and can be consumed as syrup and pills. It usually starts working after 3 hours in asthma patients. They remain effective in the body for approximately 6-12 hours after consumption.
How Does Works Dexamethasone for asthma?
It has been found to be highly effective when it comes to the treatment of the acute exacerbation of asthma. It is available as an injectable medicine as well as a 0.1% ophthalmic solution. it’s works to reduce the swelling caused by inflammation and helps asthma patients breathe comfortably. Usually, a single dose is sufficient in children to promote easy breathing, but few may require more than a single dose to help alleviate its symptoms.
- They work by mimicking the hormone effects produced through the adrenal glands. These same hormones play a significant role in regulating immune response and inflammation.
- It targets the deposit of inflammatory cells and causes the cellular membranes to stabilize so that the inflammatory mediators can be prevented from being released.
- All the above actions reduce swelling, mucus production, and redness in an individual’s airways. This helps improve breathing and airflow in asthma patients.
- It leads to the suppression of the response from the immune system and helps control asthma.
- It targets the immune system activity and prevents the exacerbations of asthma.
Benefits of Using Dexamethasone
It is a useful corticosteroid that targets inflammation, reduces it, and helps suppress the patient’s immune system response. It is extremely useful against asthma exacerbations and can provide instant relief from the severe signs and symptoms of asthma and breathing-related issues. There are potential side effects of Dexamethasone tablets; hence, it is advised to be used on a short-term basis.
Dexamethasone Wholesale Supplier also works well in emergency settings and targets the reduction of airway inflammation when an asthma attack occurs. Oral medication helps alleviate severe symptoms of asthma.
Risks and Side-effects
It is highly effective for controlling asthma symptoms, but at the same time, it may have some side effects that can still be managed. A few side effects of Dexamethasone are:
- Gain in weight
- Higher levels of blood sugar
- Higher risks of infection
- Behavioral changes
- Osteoporosis
- Hypertension
- Mood swings
Dexamethasone vs. Other Asthma Medications
Dexamethasone vs. Prednisone: Dexamethasone is usually given to asthma patients for 1-5 days, and the usual starting dose is 0.3 to 0.6 mg/kg daily. It is also one of the longest-acting glucocorticoids, with a half-life of 36-72 hours. When compared with Prednisone, it is a fast and long-acting agent in the body, while the former has a half-life of only 18-36 hours.
Dexamethasone vs. Bronchodilators: Short-Acting Beta-Agonists (SABAs) and Long-Acting Beta-Agonists (LABAs) may not replace Dexamethasone. It addresses problems associated with inflammation; whereas SABAs are not suitable for the complete treatment of inflammation, they can only offer rapid relief. On the other hand, the LABAs are also not ideal for use against the acute symptoms of asthma. They cannot replace effective corticosteroids such as Decmax 4mg (Dexamethasone), as the latter is highly recommended for fast managing inflammation and asthma.
Dexamethasone for asthma vs. Leukotriene Modifiers: Medicines like Zafirlukast and Montelukast are considered less capable than corticosteroids. They are often used as one of the many add-on therapies and not as a replacement for the effective form of corticosteroids.
Dexamethasone vs. Biologic Therapies: Medicines like Dupilumab, Omalizumab and Mepolizumab, and other biologics are suitable for specific forms of asthma or allergic asthma, and they can only be used as a therapy that is to be treated as an add-on when the other types of treatments have either failed or may not be suitable/sufficient.
How to Use Dexamethasone Safely
Dexamethasone for asthma can be used safely by:
- Following medical advice and as per the dosage amount prescribed and the duration for the treatment.
- Avoiding self-medication or attempting a dosage alteration without a doctor’s consultation.
- Using the proper dosage of the medicine depends on various factors like weight, age, and medical condition of the patient.
- Ensuring proper administration of the medicine, possibly in forms such as tablets, topical formulations, Dexamethasone injections, etc.
- Ensuring its use within the shortest required duration to ensure minimization of harmful side effects.
- Educating self about its drug interactions that include anticoagulants, NSAIDs, and various other forms of vaccines. It is essential to discuss with your health provider about all the medications one may be using and their possible interactions.
Conclusion
Dexamethasone for asthma can be used to control and manage asthma and a few other associated respiratory problems in adults and children. However, maximum benefits can be fetched by making lifestyle changes (proper diet and workout). Long-term use may require regular monitoring of the levels of the blood sugar in an individual, blood pressure as well as bone density so that side effects can be managed. Overdose or worsening of side effects require immediate medical attention.
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