Description

What is LuciOlap 150Mg?

The brand name for the medicine Olaparib, LuciOlap 150Mg is a kind of cancer medication also identified as the PARP inhibitor. It is an active medication utilized for the treatment of different cancer types that include:  

• Breast cancer
• Ovarian cancer
• Pancreatic cancer
• Fallopian tube cancer
• Primary Peritoneal Cancer
• Prostate cancer

It can treat all kinds of cancer, specifically the ones with genetic mutations such as BRCA.

LuciOlap 150 Mg is a prescription-only PARP inhibitor.

LuciOlap 150Mg Tablet Uses

LuciOlap 150 Mg is one of the most effective and widely used targeted anti-cancer therapy that contains Olaparib. It is a PARP inhibitor that is specifically prescribed for the type of cancer-related to BRCA1/BRCA2 and various other gene mutations.

It is useful in the management of multiple kinds of cancer.

Ovarian cancer: Used as a good maintenance treatment for adults suffering from platinum-sensitive relapsed ovarian, primary peritoneal cancer or that of the fallopian tube. It involves the BRCA mutations. Advanced ovarian cancer cases also involve its use post-chemotherapy.

Breast cancer: Used for HER2-negative metastatic breast cancer in those patients that have the germline BRCA mutation. It may be an effective treatment in patients in which cancer has spread uncontrollably. When hormone or chemotherapy has also failed in such patients,  Olaparib 150Mg may be used.

Pancreatic Cancer: First-line treatment for patients with germline BRCA mutations. It is also suitable for patients with metastatic pancreatic cancer. It may be used in patients after the chemotherapy based on platinum.

Prostrate cancer: Used in mCRPC patients that are known to have the HRR gene mutations. In such patients when their case has progressed even after treatment with abiraterone and enzalutamide, LuciOlap 150 Mg may be recommended.

LuciOlap 150Mg Tablet Working, Mechanism of Action and Pharmacology

LuciOlap 150 Mg is used as Olaparib medicine. It works as a PARP inhibitor.

Mechanism of action:

• Damage repair inhibition of DNA (single as well as the double-strand breaks)
• BRCA-mutated Cells – synthetic lethality (Olaparib is known to block PARP, these cells fail to repair the damaged DNA and finally fail to survive)
• Olaparib is also known to be toxic to the cells of Cancer with a significant deficiency in HR and spares out normal cells.

Pharmacology:

• Class of drug: PARP inhibitor
• Administration: Oral formulation
• Binding of proteins: 82%
• Metabolism: CYP3A4 enzyme (liver)
• Half life: Approx. 11-12 hours
• Excretion: Through Feces and urine

LuciOlap 150Mg Tablet – Composition and Active Ingredients

LuciOlap 150Mg has Olaparib as its major ingredient and presents as 150mg hence the medicine may also be identified as Olaparib 150Mg. It is an oral tablet belonging to the class of PARP inhibitors. Its role is to target all the PARP-1 as well as the PARP-2 enzymes associated with DNA repair.

Inactive components may involve Microcrystalline cellulose, Hydroxypropyl cellulose, Lactose monohydrate, Sodium starch glycolate, Magnesium stearate, Colloidal silicon dioxide, and other film-coating materials such as titanium dioxide, hypromellose, and iron oxide.

LuciOlap 150Mg Tablet – Side-effects

Common: Nausea, vomiting, fatigue, headache, poor appetite, dizziness, diarrhea, Anemia, low WBCs, and lower platelet counts.

Less severe: Constipation, poor digestion, dry mouth, pain in the abdomen, taste change, Skin Reactions, rash, breathlessness, and cough.

Serious: Myelodysplastic Syndrome (MDS), Pneumonitis, Acute Myeloid Leukemia (AML), bone marrow suppression, or severe anemia.

Monitoring of the condition is recommended in patients prone to leukopenia, anemia, and thrombocytopenia. Liver and kidney function must be evaluated too. Possible Signs of bleeding and infection must be checked regularly.

Side effects of LuciOlap 150Mg can be managed by:

• Taking the tablet with a meal to target nausea
• Maintaining proper hydration for the management of diarrhea
• Using antiemetics only if prescribed
• Consulting with a physician if dizziness and fatigue occur or worsen

When to call the doctor? In case of persistent vomiting, high fever, infection, bleeding, breathlessness, painful chest, or serious fatigue.

How to Use LuciOlap 150Mg Tablet?

• LuciOlap 150 Mg may be taken twice a day but only when an oncologist has prescribed the dose.
• To be swallowed completely with water, it is an oral medication
• May be taken without or without any kind of meal
• Do not double its dose to complete the missed dose

Precautions

• Genetic testing is needed and should be used in patients with BRCA mutations only or in patients with defects in the HRR gene.
• Blood count monitoring must be done with CBC to evaluate the conditions associated with low white cells and low platelets.
• Olaparib 150Mg may not be suitable for pregnant women as its dose may harm the unborn baby or affect the fetus’s development.
• Breastfeeding mothers should also seek medical advice.
• Caution is to be advised in patients with severe and moderate kidney or liver impairment, dose adjustments may be needed.
• Drug interactions are possible with strong CYP3A4 inhibitors or inducers as they may boost intoxicity and target drug efficacy.
• Make sure to keep your physician informed about all types of different prescription drugs and also non-prescription medicines patient may be taking along with any herbal supplements.
• Avoid using heavy machinery or driving to prevent episodes of dizziness.
• Usually easily tolerated by most elderly patients but caution should be taken with regular blood count monitoring.
• Storage at 15–30°C and prevent it from direct light, heat, or moisture.

Where to Buy LuciOlap 150 Mg from?

LuciOlap 150 Mg can be ordered from Medzsupplier, a trusted and genuine online pharmacy that stocks the best and most affordable medicines to combat infections, cancer, and other similar treatments.