Niclobest 500 (Niclosamide)

Active Ingredient	Niclosamide
Dosage Form	Tablet
Manufacturer	Kachhela Medex Pvt. Ltd.
Packaging	10 tablets in 1 strip
Strength	500mg
Indication	Worm infections
Country of Origin	India

INQUIRE ABOUT Niclobest 500 (Niclosamide)

INQUIRE ABOUT Niclobest 500 (Niclosamide)

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Description

What is Niclobest 500 (Niclosamide)?

Niclobest 500 contains Niclosamide as its primary ingredient, which is useful in treating worm infections. It is one of the most effective and useful drugs used as antihelminthics, especially for treating tapeworm infections. It is indicated for use in treating tapeworms and infections that include intestinal flukes. Additionally, it is used as a molluscicide to stop and manage schistosomiasis.

Mechanism of action

Niclobest 500 (Niclosamide) works in the body by killing and preventing further growth of the tapeworms that come in contact. Adult worms in the body are killed fast through the rapid stimulation of ATPase activity. The worms that have been killed usually pass out through the stools and may also be destroyed completely or partially in the intestine of the patient’s body. It can work in the patient’s body as molluscicide by binding into the DNA and causing damage.

How to use Niclobest 500 Mg?

• Niclobest 500 Mg can be taken on an empty stomach, but it is also advisable to consume it with a lighter meal to eliminate any possibility of stomach problems.
• Niclobest 500 Mg is meant to be chewed and crushed before having them swallowed with some water.
• When administered to a patient who is young enough to swallow, it can always be given in powdered form.
• Patients who are taking this for treatment against beef or fish tapeworms should take it strictly as advised by the doctor so that the infection is cleared properly and completely.
• Usually, one dose of  this medicine is sufficient but in few patients, the cycle may be repeated in order to completely kill the infection.
• Patients taking this medicine for the treatment of dwarf tapeworms must consume it for the full course of the treatment (which is usually seven days).
• Buy Niclosamide 500Mg only from trusted Niclobest Exporter and Niclobest supplier that stocks genuine and safe Niclosamide 500 Mg Tablet.

Dosage and Administration

Patients and children over the age of 2 must stick to its general dose of 2 grams (to be counted as a single dosage). The dosage may still vary depending on how severe the infection has turned out to be in a patient and various other factors.

• 2 grams as a single dose for adults fighting off fish tapeworms and beef tapeworms.
• For youngsters, the dosage is often determined by their whole body weight.

Fish or beef Tapeworms

• Children weighing 11-34 kg should take 1 gm as a single dose, with the possibility of repeating the medicine after 7 days in case the infection has not been treated.
• Children over 34 kg should take an ideal dose of not less than 1.5 grams as a single dose. When the infection has not been treated, the treatment cycle may be repeated after seven days.

Dwarf Tapeworms

• Patients seeking treatment for dwarf tapeworms must take 2 grams of the ideal dosage for a single time.
• The treatment plan and dosage depend on the weight of the children.
• 1 gram is the ideal dosage amount for the first day in children weighing 11-34 kg. Thereafter, the dosage can be reduced to half (500 miligrams for the rest of the 6 days as a single dose).
• 1.5 grams is the ideal dose for children over 34 kgs, which can be reduced to 1 gram daily for another 6 days.

Commons side effects of Niclobest 500 Mg

Common side effects of Niclobest 500 Mg are:

• Discomfort in the abdominal region
• Nausea
• Diarrhea
• Skin rash and itching
• Dizziness
• Headache

In case of severe side effects, one must seek medical assistance.

Precautions

• Patients allergic to its primary ingredient, Niclosamide, must avoid it.
• The safety and efficacy of Niclobest 500 Mg are not clear in pregnant and breastfeeding women; hence, doctor consultation is the only way to approach consultation in such conditions.
• Before using it, you must discuss any pre-existing conditions, such as problems with your kidneys, liver, or heart, with your doctor.
• Patients consuming antacids must use it cautiously as Niclobest 500 Mg may affect the absorption of this medicine.
• Albendazole and Praziquantel may be used as alternatives to this medicine against tapeworm infestations.
• The medicine should be properly stored in tight containers and carefully kept away from direct sunlight and moisture, which may affect its quality and efficacy.

Niclosamide: WHO’s Essential Medicine

Niclosamide has been listed as one of the essential medications by the WHO. It has been approved as one of the chewable antihelminthic agents for treating tapeworm infections for more than 40 years. With their action, the proximal segment, as well as the scolex of the tapeworms, are killed. It has been known to stop the growth of chemical substances and shows its potential against various medical concerns, including cancer, chronic problems, and viral and bacterial infections.

It has also been in trial (the status of the clinical trials can be accessed on WHO’s website/NCT) to prove its efficacy in the fight against COVID-19. It has emerged as a “multifunctional drug”.

Niclosamide in COVID-19

Niclosamide has been marked as a multifunctional drug and has shown preclinical activities in various disease models, from diseases like cancer to multiple infections. It can be stated that the exaggerated levels of immune response have been one of the root causes of rising mortality rates in COVID-19 patients, along with bacterial infestations. The COVID-19 infection in patients has also grown as a result of acute respiratory distress syndrome. Clinical trials are ongoing, but future advancements can prove to be a significant milestone in the fight against the pandemic for the upcoming generations.

Where can you Buy Niclobest 500 Mg and Niclosamide 500Mg?

Buy Niclobest 500 Mg online from Medzsupplier, a leading Niclobest 500 Mg Distributor and Niclosamide Wholesaler that stocks and sells genuine Niclobest Wholesale packs at affordable prices.